Trial intelligence / Profile preview

DEP-Ru salvage therapy for refractory or relapsed hemophagocytic lymphohistiocytosis

ChiCTR1800016124Phase 3Recruiting

Sponsor
Beijing Friendship Hospital
Start
Jun 2018
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Countries
1
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Overview

Phase 3, open-label, single-arm trial of ruxolitinib, pegylated liposomal doxorubicin, etoposide and methylprednisolone in haemophagocytic lymphohistiocytosis (HLH), sponsored by Beijing Friendship Hospital. Primary endpoints: sCD25, neutrophil and 9 more. Started Jun 2018; status: recruiting.

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Drugs

ruxolitinibpegylated liposomal doxorubicinetoposidemethylprednisolone
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Conditions

haemophagocytic lymphohistiocytosis (HLH)

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