Trial intelligence / Profile preview

Pyrotinib + trastuzumab + docetaxel + carboplatin versus trastuzumab + docetaxel + carboplatin as neoadjuvant therapy for locally advanced HER2-positive breast cancer

ChiCTR1900026200Phase 3Not yet recruiting

Sponsor
First Hospital of China Medical University
Start
Oct 2019
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Phase 3, randomised, open-label trial of pyrotinib, trastuzumab, docetaxel and carboplatin in breast cancer (2 arms), sponsored by First Hospital of China Medical University. Primary endpoint: Total pathologic complete response rate. Planned start Oct 2019; status: not yet recruiting.

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Drugs

pyrotinibtrastuzumabdocetaxelcarboplatin
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Conditions

breast cancer

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