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Pyrotinib + trastuzumab versus pertuzumab + trastuzumab for residual HER2-positive breast cancer after neoadjuvant therapy

ChiCTR2000040866Phase 4Recruiting

Sponsor
Suining Central Hospital
Start
Jan 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial in breast cancer comparing Pyrotinib + trastuzumab with Pertuzumab + trastuzumab (2 arms). Primary endpoint: Invasive disease-free survival. Started Jan 2021; status: recruiting.

02

Drugs

pyrotinibpertuzumabtrastuzumab
03

Conditions

breast cancer

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