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Pyrotinib + trastuzumab + vinorelbine neoadjuvant therapy for HER2-positive breast cancer with poor response to prior TCHP

ChiCTR2100047650Phase 2Not yet recruiting

Sponsor
Chongqing University Cancer Hospital
Start
Jul 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of pyrotinib, trastuzumab and vinorelbine in breast cancer, sponsored by Chongqing University Cancer Hospital. Primary endpoint: Pathological complete response rate. Planned start Jul 2021; status: not yet recruiting.

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Drugs

pyrotinibtrastuzumabvinorelbine
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Conditions

breast cancer

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