Trial intelligence / Profile preview

Pyrotinib + Trastuzumab + SHR6390 + Letrozole for neoadjuvant treatment of stage II–III triple-positive breast cancer

ChiCTR2200055628Phase 2Recruiting

Sponsor
Shengjing Hospital of China Medical University
Start
Feb 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of pyrotinib, trastuzumab, dalpiciclib and letrozole in breast cancer, sponsored by Shengjing Hospital of China Medical University. Primary endpoint: Total pathological complete response (tpCR). Started Feb 2022; status: recruiting.

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Drugs

pyrotinibtrastuzumabdalpiciclibletrozole
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Conditions

breast cancer

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