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Pyrotinib + trastuzumab + nab-paclitaxel as neoadjuvant therapy for stage II–III HER2-positive breast cancer

ChiCTR2200056592Phase 4Recruiting

Sponsor
Mudanjiang Cancer Hospital
Start
Dec 2020
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label, single-arm trial of pyrotinib, trastuzumab and nab-paclitaxel in breast cancer, sponsored by Mudanjiang Cancer Hospital. Primary endpoint: pathological complete response rate. Started Dec 2020; status: recruiting.

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Drugs

pyrotinibtrastuzumabnab-paclitaxel
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Conditions

breast cancer

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