Trial intelligence / Profile preview

Chemotherapy-free neoadjuvant trastuzumab + pyrotinib + dalpiciclib ± letrozole for HER2-positive early breast cancer

ChiCTR2200060748Phase 4Not yet recruiting

Sponsor
Xiangya Hospital, Central South University
Start
Jun 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of trastuzumab, pyrotinib, dalpiciclib and letrozole in breast cancer, sponsored by Xiangya Hospital, Central South University. Primary endpoint: Pathological complete response rate. Planned start Jun 2022; status: not yet recruiting.

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Drugs

trastuzumabpyrotinibdalpiciclibletrozole
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Conditions

breast cancer

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