Trial intelligence / Profile preview

Neoadjuvant dalpiciclib + pyrotinib + trastuzumab + letrozole for HER2-positive, hormone receptor-positive breast cancer

ChiCTR2200065170Phase 4Not yet recruiting

Sponsor
First Affiliated Hospital of Soochow University
Start
Oct 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of dalpiciclib, pyrotinib, trastuzumab and letrozole in breast cancer, sponsored by First Affiliated Hospital of Soochow University. Primary endpoint: Total pathological complete response. Planned start Oct 2022; status: not yet recruiting.

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Drugs

dalpiciclibpyrotinibtrastuzumabletrozole
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Conditions

breast cancer

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