Trial intelligence / Profile preview

Pyrotinib-based versus trastuzumab + pertuzumab taxane neoadjuvant therapy for HER2-positive early or locally advanced breast cancer

ChiCTR2400079934Phase 4Recruiting

Sponsor
Foshan First People's Hospital
Start
Jan 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
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Overview

Phase 4, randomised, open-label trial of pyrotinib, trastuzumab and pertuzumab in breast cancer (3 arms), sponsored by Foshan First People's Hospital. Primary endpoint: Pathological complete response rate. Started Jan 2024; status: recruiting.

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Drugs

pyrotinibtrastuzumabpertuzumab
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Conditions

breast cancer

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