Trial intelligence / Profile preview

Ruxolitinib plus dexamethasone versus HLH-1994 for newly diagnosed adult hemophagocytic lymphohistiocytosis

ChiCTR2400085248Phase 2Not yet recruiting

Sponsor
First Affiliated Hospital, Zhejiang University School of Medicine
Start
Jun 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of ruxolitinib, dexamethasone and etoposide in haemophagocytic lymphohistiocytosis (HLH) (2 arms), sponsored by First Affiliated Hospital, Zhejiang University School of Medicine. Primary endpoint: overall survival. Planned start Jun 2024; status: not yet recruiting.

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Drugs

ruxolitinibdexamethasoneetoposide
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Conditions

haemophagocytic lymphohistiocytosis (HLH)

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