Trial intelligence / Profile preview

Neoadjuvant trastuzumab biosimilar + pertuzumab biosimilar with XELOX for HER2-positive locally advanced rectal cancer

ChiCTR2500099967Phase 2Not yet recruiting

Sponsor
Peking Union Medical College Hospital
Start
Apr 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of trastuzumab, pertuzumab, oxaliplatin and capecitabine in rectal adenocarcinoma, sponsored by Peking Union Medical College Hospital. Primary endpoint: Complete response rate. Planned start Apr 2025; status: not yet recruiting.

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Drugs

trastuzumabpertuzumaboxaliplatincapecitabine
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Conditions

rectal adenocarcinoma

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