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Pyrotinib + nab-paclitaxel + trastuzumab as neoadjuvant therapy for HER2-positive early or locally advanced breast cancer

ChiCTR2500100648Phase 4Not yet recruiting

Sponsor
Huaihe Hospital of Henan University
Start
Apr 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label, single-arm trial of pyrotinib, paclitaxel and trastuzumab in breast cancer, sponsored by Huaihe Hospital of Henan University. Primary endpoint: Pathologic complete response. Planned start Apr 2025; status: not yet recruiting.

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Drugs

pyrotinibpaclitaxeltrastuzumab
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Conditions

breast cancer

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