Trial intelligence / Profile preview

THPy vs THP as first-line therapy for advanced HER2-positive breast cancer

ChiCTR2500101511Phase 4Recruiting

Sponsor
Anhui Provincial Tumor Hospital
Start
May 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial of pyrotinib, trastuzumab, pertuzumab and trastuzumab rezetecan in breast cancer (2 arms), sponsored by Anhui Provincial Tumor Hospital. Primary endpoint: progression-free survival. Started May 2025; status: recruiting.

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Drugs

pyrotinibtrastuzumabpertuzumabtrastuzumab rezetecan
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Conditions

breast cancer

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