Trial intelligence / Profile preview

Pyrotinib + trastuzumab + nab-paclitaxel + carboplatin neoadjuvant therapy for HER2-positive/HR-positive early breast cancer

ChiCTR2500102478Phase 2Recruiting

Sponsor
The Fifth Affiliated Hospital of Sun Yat-sen University
Start
May 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of pyrotinib, trastuzumab, paclitaxel and carboplatin in breast cancer, sponsored by The Fifth Affiliated Hospital of Sun Yat-sen University. Primary endpoint: pathological complete response rate. Started May 2025; status: recruiting.

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Drugs

pyrotinibtrastuzumabpaclitaxelcarboplatin
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Conditions

breast cancer

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