Trial intelligence / Profile preview

Real-world comparison of THP versus TH + HER2-TKI regimens in HER2-positive advanced breast cancer

ChiCTR2500103653Phase 4Not yet recruiting

Sponsor
Union Hospital
Start
Jun 2025
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label trial of pertuzumab, trastuzumab, docetaxel, paclitaxel, pyrotinib and 2 more in breast cancer (2 arms), sponsored by Union Hospital. Primary endpoints: Progression-free survival and Incidence of adverse drug reactions and adverse events. Planned start Jun 2025; status: not yet recruiting.

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Drugs

pertuzumabtrastuzumabdocetaxelpaclitaxelpyrotinib
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Conditions

breast cancer

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