Trial intelligence / Profile preview

Toripalimab + pertuzumab/trastuzumab SC + nab-paclitaxel neoadjuvant therapy in HER2-positive stage II–III breast cancer

ChiCTR2500108585Phase 2Recruiting

Sponsor
Southwest Hospital of Army Medical University
Start
Sep 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of toripalimab, pertuzumab, trastuzumab, paclitaxel and trastuzumab emtansine in breast cancer, sponsored by Southwest Hospital of Army Medical University. Primary endpoint: Total pathological complete response (tpCR). Started Sep 2025; status: recruiting.

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Drugs

toripalimabpertuzumabtrastuzumabpaclitaxeltrastuzumab emtansine
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Conditions

breast cancer

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