Trial intelligence / Profile preview

Kudosil + Culmerciclib + trastuzumab + pertuzumab neoadjuvant therapy in HR+/HER2+ breast cancer

ChiCTR2600121242Phase 2Recruiting

Sponsor
Jiangsu Provincial People's Hospital
Start
Mar 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of inavolisib, culmerciclib, letrozole, trastuzumab and pertuzumab in breast cancer, sponsored by Jiangsu Provincial People's Hospital. Primary endpoint: tpCR (total pathological complete response). Started Mar 2026; status: recruiting.

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Drugs

inavolisibculmerciclibletrozoletrastuzumabpertuzumab
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Conditions

breast cancer

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