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Phase III neoadjuvant KN026 + HB1801 ± carboplatin versus trastuzumab + pertuzumab + docetaxel ± carboplatin in HER2-positive early or locally advanced breast cancer

CTR20244675Phase 3Active

Sponsor
Shanghai Jinmante Biotechnology Co., Ltd.
Start
Dec 2024
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of anbenitamab, albumin-bound docetaxel, trastuzumab, pertuzumab, docetaxel and 1 more in breast cancer (2 arms), sponsored by Shanghai Jinmante Biotechnology Co., Ltd. Primary endpoint: Total pathologic complete response. Started Dec 2024; status: active.

02

Drugs

anbenitamabalbumin-bound docetaxeltrastuzumabpertuzumabdocetaxel
03

Conditions

breast cancer

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