Trial intelligence / Profile preview

Peri-operative anti-HER2 therapy biological study in early HER2-positive breast cancer

ISRCTN15004993Phase 3Completed

Sponsor
The University of Manchester
Start
Apr 2010
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
01

Overview

Phase 3, randomised, open-label trial of trastuzumab and lapatinib in breast cancer (3 arms), sponsored by The University of Manchester. Primary endpoints: Increase in apoptosis and Fall in proliferation between diagnosis and surgery. Started Apr 2010; status: completed.

02

Drugs

trastuzumablapatinib
03

Conditions

breast cancer

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