Trial intelligence / Profile preview

Adalimumab versus methotrexate for moderate chronic plaque psoriasis

ISRCTN18260393Phase 3Recruiting

Sponsor
Newcastle Clinical Trials Unit
Start
Sep 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised trial in psoriasis comparing Adalimumab with Methotrexate control (2 arms). Primary endpoints: PASI 75 at 16 weeks and Incremental cost per QALY gained at 24 weeks. Started Sep 2026; status: recruiting.

02

Drugs

adalimumabmethotrexate
03

Conditions

psoriasis

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