Trial intelligence / Profile preview

3-Pillars combination treatment for early hormone receptor-positive HER2-positive breast cancer

ISRCTN37422164Phase 2Completed

Sponsor
University of Liverpool
Start
Aug 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
01

Overview

Phase 2, open-label trial of tucatinib, palbociclib, letrozole and trastuzumab in breast cancer, sponsored by University of Liverpool. Primary endpoint: Pathological complete response rate. Started Aug 2024; status: completed.

02

Drugs

tucatinibpalbociclibletrozoletrastuzumab
03

Conditions

breast cancer

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