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Master Protocol Trial of Tirzepatide and Retatrutide in Adults With MASLD at High Risk for Major Adverse Liver Outcomes

jRCT2021250031Recruiting

Sponsor
Eli Lilly and Company
Start
Apr 2026
Modality
Recombinant Proteins and Enzymes, Peptides
01

Overview

Randomised trial of tirzepatide and retatrutide in metabolic dysfunction-associated steatotic liver disease (MASLD) (4 arms), sponsored by Eli Lilly and Company. Primary endpoint: Time to First Occurrence of Any Component of the Composite Endpoint for Major Adverse Liver Outcomes (MALO). Started Apr 2026; status: recruiting.

02

Drugs

03

Conditions

metabolic dysfunction-associated steatotic liver disease (MASLD)

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