Trial intelligence / Profile preview

Phase 2 basket study of tucatinib plus trastuzumab in previously treated HER2-altered advanced solid tumors

jRCT2031210113Phase 2Active, not recruiting

Sponsor
Seagen Inc.
Start
Jul 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
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Overview

Phase 2, open-label trial of tucatinib, trastuzumab and fulvestrant in Cervical Cancer (CC), uterine cancer, biliary cancer and 4 more (2 arms), sponsored by Seagen Inc. Primary endpoint: Confirmed objective response rate. Started Jul 2021; status: active, not recruiting.

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Drugs

tucatinibtrastuzumabfulvestrant
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Conditions

Cervical Cancer (CC)uterine cancerbiliary cancertransitional cell carcinoma (TCC)non-small cell lung cancer (NSCLC)

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