Trial intelligence / Profile preview

ADORE: Novel ruxolitinib combinations in myelofibrosis

jRCT2031220109Phase 2Completed

Sponsor
Novartis
Start
Jun 2022
Modality
Small Molecules
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Overview

Phase 2, randomised, open-label trial of ruxolitinib in myelofibrosis (MF), primary myelofibrosis (PMF), post-essential thrombocythemia myelofibrosis (PET-MF) and 1 more (14 arms), sponsored by Novartis. Primary endpoints: Incidence of dose limiting toxicities within the first 2 cycles and Response rate at the end of cycle 6 or cycle 8. Started Jun 2022; status: completed.

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Drugs

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Conditions

myelofibrosis (MF)primary myelofibrosis (PMF)post-essential thrombocythemia myelofibrosis (PET-MF)post-polycythemia vera myelofibrosis (PPV-MF)

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