Trial intelligence / Profile preview

MOUNTAINEER-03 first-line HER2-positive metastatic colorectal cancer study

jRCT2031220580Phase 3Recruiting

Sponsor
Pfizer
Start
Jun 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, open-label trial of tucatinib, trastuzumab, oxaliplatin, levoleucovorin, fluorouracil and 2 more in colorectal cancer (CRC) and colorectal adenocarcinoma (2 arms), sponsored by Pfizer. Primary endpoint: Progression-free survival. Started Jun 2023; status: recruiting.

02

Drugs

tucatinibtrastuzumaboxaliplatinlevoleucovorinfluorouracil
03

Conditions

colorectal cancer (CRC)colorectal adenocarcinoma

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