Trial intelligence / Profile preview

REFINE: Navitoclax Alone or with Ruxolitinib in Myelofibrosis

jRCT2041210029Active, not recruiting

Sponsor
AbbVie Inc.
Start
Jul 2021
Modality
Small Molecules
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Overview

Open-label trial of navitoclax and ruxolitinib in myelofibrosis (MF), primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) and 1 more (2 arms), sponsored by AbbVie Inc. Primary endpoint: SVR35 at Week 24. Started Jul 2021; status: active, not recruiting.

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Drugs

navitoclaxruxolitinib
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Conditions

myelofibrosis (MF)primary myelofibrosis (PMF)post-polycythemia vera myelofibrosis (PPV-MF)post-essential thrombocythemia myelofibrosis (PET-MF)

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