Trial intelligence / Profile preview

SELECT-SWITCH: upadacitinib versus adalimumab in rheumatoid arthritis after inadequate response or intolerance to one TNF inhibitor

jRCT2071230022Phase 4Active, not recruiting

Sponsor
AbbVie Inc.
Start
Sep 2023
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
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Overview

Phase 4, randomised, double-blind trial of upadacitinib, adalimumab and methotrexate in rheumatoid arthritis (RA) (2 arms), sponsored by AbbVie Inc. Primary endpoint: Percentage of participants achieving DAS28-CRP <= 3.2. Started Sep 2023; status: active, not recruiting.

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Drugs

upadacitinibadalimumabmethotrexate
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Conditions

rheumatoid arthritis (RA)

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