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Adjuvant trastuzumab + pertuzumab + taxane vs trastuzumab emtansine + pertuzumab after anthracyclines in operable HER2-positive breast cancer

jRCT2080222371Phase 3Completed

Sponsor
Chugai Pharmaceutical Co., Ltd.
Start
Jan 2014
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, open-label trial of trastuzumab emtansine, pertuzumab and trastuzumab in breast cancer (2 arms), sponsored by Chugai Pharmaceutical Co., Ltd. Primary endpoint: Invasive disease-free survival (IDFS). Started Jan 2014; status: completed.

02

Drugs

trastuzumab emtansinepertuzumabtrastuzumab
03

Conditions

breast cancer

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