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Phase II chemotherapy plus immune checkpoint inhibitor followed by conversion surgery for stage IV gastric or gastroesophageal junction adenocarcinoma with a single non-curable factor

jRCTs051220065Phase 2Recruiting

Sponsor
Japan Society of Clinical Oncology
Start
Oct 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
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Overview

Phase 2, open-label trial of pembrolizumab, nivolumab, trastuzumab, oxaliplatin, tegafur and 3 more in gastric cancer (GC) and gastroesophageal junction adenocarcinoma (2 arms), sponsored by Japan Society of Clinical Oncology. Primary endpoint: R0 resection rate. Started Oct 2022; status: recruiting.

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Drugs

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Conditions

gastric cancer (GC)gastroesophageal junction adenocarcinoma

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