Trial intelligence / Profile preview

Randomized risk-stratified pediatric Crohn's disease trial comparing methotrexate with thiopurines or adalimumab for maintenance of remission

MOH_2017-09-03_000771Phase 4Recruiting

Sponsor
PIBD-Net
Start
Oct 2016
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial of methotrexate, mercaptopurine and adalimumab in Crohn's disease (4 arms), sponsored by PIBD-Net. Primary endpoints: Maintenance of remission over 1 year, Maintenance of remission over 1 year in low-risk group and 1 more. Started Oct 2016; status: recruiting.

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Drugs

methotrexatemercaptopurineadalimumab
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Conditions

Crohn's disease

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