Trial intelligence / Profile preview

Phase 3b randomized study of mirikizumab with tirzepatide versus mirikizumab with placebo in adults with moderately to severely active ulcerative colitis and overweight or obesity

MOH_2025-05-08_014072Phase 3Not yet recruiting

Sponsor
Eli Lilly and Company
Start
May 2025
Modality
Recombinant Proteins and Enzymes, Peptides, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
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Overview

Phase 3, randomised trial in autoimmune colitis, obesity and Overweight comparing OMVOH + MOUNJARO with OMVOH + placebo (2 arms). Primary endpoint: Participants achieving clinical remission and at least 10% body weight reduction. Planned start May 2025; status: not yet recruiting.

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Drugs

tirzepatidemirikizumab
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Conditions

autoimmune colitisobesityOverweight

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