Trial intelligence / Profile preview

Carboplatin, Gemcitabine, and Capecitabine in CUP

NCT00148135Phase 2

Key facts

Status
Terminated
Start
May 2001
Primary completion
Apr 2006
Countries
1
Sponsor
University of Michigan Rogel Cancer Center
Modality
DNA Intercalators/Alkylators, Irreversible Covalent Inhibitors, RNA-Targeting Small Molecules
Conditions
carcinoma of unknown primary (CUP)
01

Overview

Phase 2, open-label trial of carboplatin, gemcitabine and capecitabine in carcinoma of unknown primary (CUP), sponsored by University of Michigan Rogel Cancer Center. Primary endpoint: Objective Response Rate. Started May 2001; status: terminated.

02

Design

Study design
Non-randomizedOpen-label
03

Who it enrols

Patients with histologically confirmed carcinoma of unknown primary (CUP) who are not candidates for specific subset treatment, have measurable disease, and adequate organ function.

04

Endpoints

Primary

  • Objective Response Rate

Secondary

  • Progression-Free Survival

  • Overall Survival

  • Toxicity

  • 1-Year Survival Rate

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