Trial intelligence / Profile preview

ALTAIR: Three ART regimens in treatment-naive HIV

NCT00335322Phase 4

Key facts

Status
Completed
Start
Feb 2007
Primary completion
Mar 2011
Sponsor
The Kirby Institute
Modality
Small Molecules
Conditions
human immunodeficiency virus infection (HIV)
01

Overview

Phase 4, randomised, open-label trial of zidovudine and abacavir in human immunodeficiency virus infection (HIV), sponsored by The Kirby Institute. Started Feb 2007; status: completed.

02

Design

Study design
RandomizedOpen-label
03

Registry description

In treatment naïve HIV infected subjects, combination antiretroviral therapy including efavirenz combined with tenofovir and emtricitabine will offer non-inferior antiretroviral efficacy over 48 weeks, compared to either atazanavir boosted with ritonavir combined with tenofovir and emtricitabine or tenofovir and emtricitabine combined with zidovudine and abacavir, as assessed by change from baseline plasma HIV-1 RNA viral load.

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