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Propranolol for catabolism in trauma patients
NCT00356187Phase 2
Key facts
- Status
- Terminated
- Start
- Feb 2006
- Primary completion
- Jan 2009
- Countries
- 1
- Sponsor
- Denver Health
- Modality
- Small Molecules
- Drugs
- propranolol
- Conditions
- psychological trauma
01
Overview
Phase 2, randomised, open-label trial of propranolol in psychological trauma, sponsored by Denver Health. Primary endpoint: Resting Energy Expenditure. Started Feb 2006; status: terminated.
02
Design
- Study design
- RandomizedOpen-label
03
Who it enrols
Severely injured trauma patients (ISS > 25) who are ventilated, resuscitated, and stable at 48 hours post-injury.
04
Endpoints
Primary
Resting Energy Expenditure
Secondary
Protein Metabolism Measurements
Neuroendocrine and Immunoinflammatory Measurements
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