Trial intelligence / Profile preview

COMFORT-II: Ruxolitinib vs Best Available Therapy in Myelofibrosis

NCT00934544Phase 3Completed

Sponsor
Novartis
Start
Jul 2009
Primary completion
Mar 2015
Modality
Small Molecules
Countries
9
01

Overview

Phase 3, randomised, open-label trial of ruxolitinib in primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) and post-essential thrombocythemia myelofibrosis (PET-MF) (2 arms), sponsored by Novartis. Primary endpoint: Percentage of Participants With at Least 35% Reduction in Spleen Volume From Baseline at Week 48. Started Jul 2009; status: completed.

02

Drugs

03

Conditions

primary myelofibrosis (PMF)post-polycythemia vera myelofibrosis (PPV-MF)post-essential thrombocythemia myelofibrosis (PET-MF)

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