Trial intelligence / Profile preview

D-cycloserine + CBT + NRT for Smoking Cessation

NCT01842334Phase 2

Key facts

Status
Terminated
Start
Apr 2013
Primary completion
Aug 2017
Countries
1
Sponsor
McLean Hospital
Modality
Covalent Small Molecules, Classical Binding Small Molecules, Nucleic Acid-Directed Small Molecules
Conditions
nicotine dependence
01

Overview

Phase 2, randomised, double-blind trial in nicotine dependence comparing D-cycloserine with Placebo (2 arms). Primary endpoint: Change From Baseline in Cigarette Smoking in Treatment Seeking Nicotine Dependent Outpatients at Week 10. Started Apr 2013; status: terminated.

02

Design

2 arms
Study design
RandomizedDouble-blind
  • D-cycloserine

    250 mg D-cycloserine + CBT + NRT

  • Placebo

    Placebo + CBT + NRT

03

Endpoints

Primary

  • Change From Baseline in Cigarette Smoking in Treatment Seeking Nicotine Dependent Outpatients

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