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Carvedilol vs Metoprolol Tartrate for Rate Control in Atrial Fibrillation
NCT02251509Phase 4
Key facts
- Status
- Unknown
- Start
- Dec 2016
- Primary completion
- Sep 2017
- Countries
- 1
- Sponsor
- Creighton University
- Modality
- Small Molecules
- Drugs
- carvedilolmetoprolol
- Conditions
- Atrial fibrillation (AFib)
01
Overview
Phase 4, randomised, double-blind trial in Atrial fibrillation (AFib) comparing Carvedilol Sequence with Metoprolol Sequence (2 arms). Primary endpoint: Resting heart rate at 2 weeks. Status: unknown.
02
Design
2 arms- Study design
- RandomizedDouble-blind
Carvedilol Sequence
Carvedilol then Metoprolol (or vice versa depending on randomization)
Metoprolol Sequence
Metoprolol then Carvedilol (or vice versa depending on randomization)
03
Who it enrols
Patients with permanent atrial fibrillation and a baseline ventricular rate > 110 bpm, excluding those with low ejection fraction (<35%) or severe heart failure (NYHA Class III/IV).
04
Endpoints
Primary
Resting heart rate
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