Trial intelligence / Profile preview

ECLIPSE: Atezolizumab Combinations in ER+/HER2- Breast Cancer

NCT03395899Phase 2

Key facts

Status
Completed
Start
Dec 2017
Primary completion
Aug 2023
Countries
1
Sponsor
Queen Mary University of London
Modality
Small Molecules, Monoclonal Antibodies
Conditions
estrogen receptor-positive breast cancer (ER+)breast cancer
01

Overview

Phase 2, randomised, open-label trial of atezolizumab, cobimetinib, ipatasertib and bevacizumab in estrogen receptor-positive breast cancer (ER+) and breast cancer, sponsored by Queen Mary University of London. Started Dec 2017; status: completed.

02

Design

Study design
RandomizedOpen-label
03

Registry description

International, open label, window of opportunity phase II trial that aims to evaluate the effects of immunotherapy based treatment combinations in women with untreated, histologically confirmed, operable, ER+, HER2-negative breast cancer.

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