Trial intelligence / Profile preview

Ruxolitinib With Radiation and Temozolomide in Newly Diagnosed Grade III Gliomas and Glioblastoma

NCT03514069Phase 1Completed

Sponsor
Case Comprehensive Cancer Center
Start
Jun 2018
Primary completion
Aug 2021
Modality
Small Molecules
Countries
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Overview

Phase 1, open-label trial of ruxolitinib in glioma and glioblastoma (GBM) (2 arms), sponsored by Case Comprehensive Cancer Center. Primary endpoints: Maximum Tolerated Dose of ruxolitinib with radiation at 6 weeks and Maximum Tolerated Dose of ruxolitinib with radiation and daily Temozolomide at 6 weeks. Started Jun 2018; status: completed.

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Drugs

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Conditions

gliomaglioblastoma (GBM)

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