Trial intelligence / Profile preview

Ruxolitinib in Low-Risk Essential Thrombocythemia and Polycythemia Vera

NCT04644211Phase 2Recruiting

Sponsor
Massachusetts General Hospital
Start
Mar 2022
Primary completion
Jul 2027
Modality
Small Molecules
Countries
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Overview

Phase 2, open-label trial of ruxolitinib in essential thrombocythemia (ET) and polycythemia vera (PV) (2 arms), sponsored by Massachusetts General Hospital. Primary endpoint: Percentage of patients who achieve >50% reduction from baseline to Myeloproliferative Neoplasm Symptom Assessment Total Symptom Score at 12 weeks. Started Mar 2022; status: recruiting.

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Drugs

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Conditions

essential thrombocythemia (ET)polycythemia vera (PV)

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