Trial intelligence / Profile preview

TR^2 (Trametinib, Retifanlimab, and Ruxolitinib) in Metastatic Pancreatic Ductal Adenocarcinoma

NCT05440942Phase 1Completed

Start
Jan 2023
Primary completion
May 2025
Modality
Small Molecules, Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label trial of trametinib, ruxolitinib and retifanlimab in pancreatic ductal adenocarcinoma (PDAC) (3 arms). Primary endpoint: Recommended Phase 2 Dose at 6 months. Started Jan 2023; status: completed.

02

Drugs

trametinibruxolitinibretifanlimab
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Conditions

pancreatic ductal adenocarcinoma (PDAC)

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