Trial intelligence / Profile preview

CAN008 plus TMZ in Newly Diagnosed Glioblastoma

NCT05447195Phase 2

Key facts

Status
Unknown
Start
Oct 2021
Primary completion
Jan 2024
Countries
1
Modality
Fc-Fusion Proteins
Conditions
glioblastoma (GBM)
01

Overview

Phase 2, randomised, double-blind trial in glioblastoma (GBM) comparing CAN008 with Placebo (2 arms). Primary endpoint: Progression-Free Survival at 3 years. Status: unknown.

02

Design

2 arms
Study design
RandomizedDouble-blind
  • CAN008

    CAN008 + RT + TMZ followed by maintenance and monotherapy

  • Placebo

    Placebo + RT + TMZ followed by maintenance and monotherapy

03

Endpoints

Primary

  • Progression-Free Survival

Secondary

  • Overall Survival

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