Trial intelligence / Profile preview

Biomarker-Guided Ruxolitinib for Prevention of Chronic GVHD After Allogeneic HCT

NCT07025538Phase 1Recruiting

Sponsor
City of Hope
Start
Apr 2026
Primary completion
Jun 2028
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of ruxolitinib in graft-versus-host disease (GVHD) (2 arms), sponsored by City of Hope. Primary endpoints: Incidence of unacceptable toxicity at 28 days, Chronic graft versus host disease at 1 year and 3 more. Started Apr 2026; status: recruiting.

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Drugs

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Conditions

graft-versus-host disease (GVHD)

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