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Dexamethasone for Prolonging Spinal Anesthesia in C-Section
NCT07088146Phase 4
Key facts
- Status
- Recruiting
- Start
- Jul 2025
- Primary completion
- Oct 2025
- Countries
- 1
- Sponsor
- Rawalpindi Medical University
- Modality
- Orthosteric Ligands
- Drugs
- dexamethasone
- Conditions
- postoperative pain
01
Overview
Phase 4, randomised trial of dexamethasone in postoperative pain (2 arms), sponsored by Rawalpindi Medical University. Primary endpoint: Time for block to regress by two dermatomes in post operative period. Started Jul 2025; status: recruiting.
02
Design
2 arms- Study design
- Randomized
Group Dexamethasone
Spinal Anesthesia + IV Dexamethasone 8mg
Group Control
Spinal Anesthesia + IV Placebo (Normal Saline)
03
Who it enrols
Pregnant patients (ASA II and above) undergoing elective Cesarean section under spinal anesthesia, excluding those with gestational diabetes, diabetes mellitus, BMI >35, adrenal insufficiency, chronic steroid use, or inadequate sensory block.
04
Endpoints
Primary
Time for block to regress by two dermatomes in post operative period
Secondary
Time to rescue analgesia
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