Trial intelligence / Profile preview

Lactobacillus Plantarum in Treating Psoriasis

NCT07194200Phase 2

Key facts

Status
Recruiting
Start
Dec 2025
Primary completion
Jun 2026
Countries
1
Sponsor
Shenzhen People's Hospital
Modality
Live Biotherapeutic Products
Conditions
psoriasis
01

Overview

Phase 2, randomised, double-blind trial of lactobacillus plantarum in psoriasis (2 arms), sponsored by Shenzhen People's Hospital. Primary endpoints: Transepidermal Water Loss at 8 weeks, General appearance photography at 8 weeks and 3 more. Started Dec 2025; status: recruiting.

02

Design

2 arms
Study design
RandomizedDouble-blind
  • Experimental Group

    Lactobacillus plantarum solution

  • Control Group

    Inactivated Lactobacillus plantarum solution

03

Who it enrols

Patients aged 18-60 with psoriasis (PASI < 10), no use of medications within 6 months, and no other inflammatory/immune skin diseases or local infections.

04

Endpoints

Primary

  • Transepidermal Water Loss

  • General appearance photography

  • Dermoscopic photography

  • Completion of self-assessment questionnaires

  • Adverse reactions

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