Trial intelligence / Profile preview

COMBAT-PsA

NCT07443956Recruiting

Sponsor
NHS Greater Glasgow and Clyde
Start
Mar 2026
Primary completion
Feb 2028
Modality
Peptides, Recombinant Proteins and Enzymes, Monoclonal Antibodies
Countries
1
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Overview

Randomised trial in psoriatic arthritis (PsA), obesity and Overweight comparing Tirzepatide group, Ixekizumab group and Combined tirzepatide and ixekizumab (3 arms). Primary endpoint: Correlation of molecular changes in biopsies (skin, synovial and adipose) with weight loss at 12 weeks. Started Mar 2026; status: recruiting.

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Drugs

tirzepatideixekizumab
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Conditions

psoriatic arthritis (PsA)obesityOverweight

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