Trial intelligence / Profile preview

Ruxolitinib and Azacitidine Maintenance in AML Patients Undergoing Reduced Intensity AlloHSCT

NCT07548983Phase 1Recruiting

Sponsor
OHSU Knight Cancer Institute
Start
Apr 2026
Primary completion
Dec 2027
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of ruxolitinib and azacitidine in acute myeloid leukemia (AML), sponsored by OHSU Knight Cancer Institute. Primary endpoints: Incidence of dose limiting toxicities at 2 months and Incidence of grade 3+ treatment-related adverse events at 9 months. Started Apr 2026; status: recruiting.

02

Drugs

ruxolitinibazacitidine
03

Conditions

acute myeloid leukemia (AML)

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