Trial intelligence / Profile preview

TARA trial: tapering conventional DMARDs versus anti-TNF first in rheumatoid arthritis remission

NL-OMON41388Recruiting

Sponsor
Erasmus MC
Start
Jun 2011
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Randomised, open-label trial of etanercept, adalimumab, certolizumab pegol, golimumab and methotrexate in rheumatoid arthritis (RA) (2 arms), sponsored by Erasmus MC. Primary endpoints: Disease flare during first year and Incremental cost-effectiveness ratio. Started Jun 2011; status: recruiting.

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Drugs

etanerceptadalimumabcertolizumab pegolgolimumabmethotrexate
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Conditions

rheumatoid arthritis (RA)

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