Trial intelligence / Profile preview

TRAP feasibility study in resectable HER2-positive esophageal adenocarcinoma

NL-OMON41623Active, not recruiting

Sponsor
Amsterdam University Medical Center
Start
Apr 2014
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
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Overview

Open-label, single-arm trial of trastuzumab, pertuzumab, paclitaxel and carboplatin in esophageal adenocarcinoma (EAC) and gastroesophageal junction adenocarcinoma, sponsored by Amsterdam University Medical Center. Primary endpoint: Feasibility of preoperative treatment in terms of withdrawal rate from surgery. Started Apr 2014; status: active, not recruiting.

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Drugs

trastuzumabpertuzumabpaclitaxelcarboplatin
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Conditions

esophageal adenocarcinoma (EAC)gastroesophageal junction adenocarcinoma

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