Trial intelligence / Profile preview

EORTC phase II trial of pertuzumab + trastuzumab with or without metronomic cyclophosphamide in older patients with HER2-positive metastatic breast cancer

NL-OMON41641Phase 2Active, not recruiting

Sponsor
European Organisation for Research and Treatment of Cancer
Start
Apr 2014
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of pertuzumab, trastuzumab, cyclophosphamide and trastuzumab emtansine in breast cancer (2 arms), sponsored by European Organisation for Research and Treatment of Cancer. Primary endpoint: Progression-free survival rate at 6 months. Started Apr 2014; status: active, not recruiting.

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Drugs

pertuzumabtrastuzumabcyclophosphamidetrastuzumab emtansine
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Conditions

breast cancer

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